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TERT genetic variability and telomere length as factors affecting survival and risk in acute myeloid leukaemia

Acute myeloid leukaemia (AML) is a neoplasm of immature myeloid cells characterized by various cytogenetic alterations. The present study showed that in addition to the FLT3-ITD and NPM1 mutation status, telomere length (TL) and telomerase reverse transcriptase (TERT) gene polymorphisms may affect r...

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Detalles Bibliográficos
Autores principales:	Dratwa, Marta, Wysoczańska, Barbara, Butrym, Aleksandra, Łacina, Piotr, Mazur, Grzegorz, Bogunia-Kubik, Katarzyna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640063/ https://www.ncbi.nlm.nih.gov/pubmed/34857839 http://dx.doi.org/10.1038/s41598-021-02767-1

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