Mutant alleles differentially shape fitness and other complex traits in cattle

Mutant alleles (MAs) that have been classically recognised have large effects on phenotype and tend to be deleterious to traits and fitness. Is this the case for mutations with small effects? We infer MAs for 8 million sequence variants in 113k cattle and quantify the effects of MA on 37 complex tra...

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Detalles Bibliográficos
Autores principales: Xiang, Ruidong, Breen, Ed J., Bolormaa, Sunduimijid, Jagt, Christy J. Vander, Chamberlain, Amanda J., Macleod, Iona M., Goddard, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640064/
https://www.ncbi.nlm.nih.gov/pubmed/34857886
http://dx.doi.org/10.1038/s42003-021-02874-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640064/
https://www.ncbi.nlm.nih.gov/pubmed/34857886
http://dx.doi.org/10.1038/s42003-021-02874-9

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