Integrative epigenomics in Sjögren´s syndrome reveals novel pathways and a strong interaction between the HLA, autoantibodies and the interferon signature

Primary Sjögren’s syndrome (SS) is a systemic autoimmune disease characterized by lymphocytic infiltration and damage of exocrine salivary and lacrimal glands. The etiology of SS is complex with environmental triggers and genetic factors involved. By conducting an integrated multi-omics study, we co...

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Detalles Bibliográficos
Autores principales: Teruel, María, Barturen, Guillermo, Martínez-Bueno, Manuel, Castellini-Pérez, Olivia, Barroso-Gil, Miguel, Povedano, Elena, Kerick, Martin, Català-Moll, Francesc, Makowska, Zuzanna, Buttgereit, Anne, Pers, Jacques-Olivier, Marañón, Concepción, Ballestar, Esteban, Martin, Javier, Carnero-Montoro, Elena, Alarcón-Riquelme, Marta E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640069/
https://www.ncbi.nlm.nih.gov/pubmed/34857786
http://dx.doi.org/10.1038/s41598-021-01324-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640069/
https://www.ncbi.nlm.nih.gov/pubmed/34857786
http://dx.doi.org/10.1038/s41598-021-01324-0

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