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Mechanistic Insights Delineating the Role of Cholesterol in Epithelial Mesenchymal Transition and Drug Resistance in Cancer

Despite the significant advancements made in targeted anti-cancer therapy, drug resistance constitutes a multifaceted phenomenon leading to therapy failure and ultimately mortality. Emerging experimental evidence highlight a role of cholesterol metabolism in facilitating drug resistance in cancer. T...

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Detalles Bibliográficos
Autores principales: Abdulla, Naaziyah, Vincent, C. Theresa, Kaur, Mandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640133/
https://www.ncbi.nlm.nih.gov/pubmed/34869315
http://dx.doi.org/10.3389/fcell.2021.728325