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Roles for the 8-Oxoguanine DNA Repair System in Protecting Telomeres From Oxidative Stress

Telomeres are protective nucleoprotein structures that cap linear chromosome ends and safeguard genome stability. Progressive telomere shortening at each somatic cell division eventually leads to critically short and dysfunctional telomeres, which can contribute to either cellular senescence and agi...

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Detalles Bibliográficos
Autores principales: De Rosa, Mariarosaria, Johnson, Samuel A., Opresko, Patricia L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640134/
https://www.ncbi.nlm.nih.gov/pubmed/34869348
http://dx.doi.org/10.3389/fcell.2021.758402