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Roles for the 8-Oxoguanine DNA Repair System in Protecting Telomeres From Oxidative Stress
Telomeres are protective nucleoprotein structures that cap linear chromosome ends and safeguard genome stability. Progressive telomere shortening at each somatic cell division eventually leads to critically short and dysfunctional telomeres, which can contribute to either cellular senescence and agi...
Autores principales: | De Rosa, Mariarosaria, Johnson, Samuel A., Opresko, Patricia L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640134/ https://www.ncbi.nlm.nih.gov/pubmed/34869348 http://dx.doi.org/10.3389/fcell.2021.758402 |
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