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Ad-Apoptin-hTERTp-E1a Regulates Autophagy Through the AMPK-mTOR-eIF4F Signaling Axis to Reduce Drug Resistance of MCF-7/ADR Cells

Ad-VT (Ad-Apoptin-hTERTp-E1a) is a type of oncolytic adenovirus with dual specific tumor cell death ability. It can effectively induce cell death of breast cancer cells and has better effect when used in combination with chemotherapy drugs. However, it has not been reported whether Ad-VT reduces the...

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Detalles Bibliográficos
Autores principales: Li, Yaru, Zhu, Yilong, Han, Jicheng, Fang, Jinbo, Xiu, Zhiru, Li, Shanzhi, Li, Wenjie, Yang, Xia, Jin, Ningyi, Sun, Lili, Li, Xiao, Li, Yiquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640141/
https://www.ncbi.nlm.nih.gov/pubmed/34869595
http://dx.doi.org/10.3389/fmolb.2021.763500