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The rs2304256 Polymorphism in TYK2 Gene Is Associated with Protection for Type 1 Diabetes Mellitus

BACKGROUND: Tyrosine kinase 2 (TYK2) is a candidate gene for type 1 diabetes mellitus (T1DM) since it plays an important role in regulating apoptotic and pro-inflammatory pathways in pancreatic β-cells through modulation of the type I interferon signaling pathway. The rs2304256 single nucleotide pol...

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Detalles Bibliográficos
Autores principales: Pellenz, Felipe Mateus, Dieter, Cristine, Duarte, Guilherme Coutinho Kullmann, Canani, Luís Henrique, de Souza, Bianca Marmontel, Crispim, Daisy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Diabetes Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640150/
https://www.ncbi.nlm.nih.gov/pubmed/34225445
http://dx.doi.org/10.4093/dmj.2020.0194