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The rs2304256 Polymorphism in TYK2 Gene Is Associated with Protection for Type 1 Diabetes Mellitus
BACKGROUND: Tyrosine kinase 2 (TYK2) is a candidate gene for type 1 diabetes mellitus (T1DM) since it plays an important role in regulating apoptotic and pro-inflammatory pathways in pancreatic β-cells through modulation of the type I interferon signaling pathway. The rs2304256 single nucleotide pol...
Autores principales: | Pellenz, Felipe Mateus, Dieter, Cristine, Duarte, Guilherme Coutinho Kullmann, Canani, Luís Henrique, de Souza, Bianca Marmontel, Crispim, Daisy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Diabetes Association
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640150/ https://www.ncbi.nlm.nih.gov/pubmed/34225445 http://dx.doi.org/10.4093/dmj.2020.0194 |
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