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Sulforaphane Ameliorates Diabetes-Induced Renal Fibrosis through Epigenetic Up-Regulation of BMP-7

BACKGROUND: The dietary agent sulforaphane (SFN) has been reported to reduce diabetes-induced renal fibrosis, as well as inhibit histone deacetylase (HDAC) activity. Bone morphologic protein 7 (BMP-7) has been shown to reduce renal fibrosis induced by transforming growth factor-beta1. The aim of thi...

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Detalles Bibliográficos
Autores principales: Kong, Lili, Wang, Hongyue, Li, Chenhao, Cheng, Huiyan, Cui, Yan, Liu, Li, Zhao, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Diabetes Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640156/
https://www.ncbi.nlm.nih.gov/pubmed/34082508
http://dx.doi.org/10.4093/dmj.2020.0168