The phosphatidylglycerol phosphate synthase PgsA utilizes a trifurcated amphipathic cavity for catalysis at the membrane-cytosol interface

Phosphatidylglycerol is a crucial phospholipid found ubiquitously in biological membranes of prokaryotic and eukaryotic cells. The phosphatidylglycerol phosphate (PGP) synthase (PgsA), a membrane-embedded enzyme, catalyzes the primary reaction of phosphatidylglycerol biosynthesis. Mutations in pgsA...

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Detalles Bibliográficos
Autores principales: Yang, Bowei, Yao, Hebang, Li, Dianfan, Liu, Zhenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640168/
https://www.ncbi.nlm.nih.gov/pubmed/34901881
http://dx.doi.org/10.1016/j.crstbi.2021.11.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640168/
https://www.ncbi.nlm.nih.gov/pubmed/34901881
http://dx.doi.org/10.1016/j.crstbi.2021.11.005

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