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A novel CD34-derived hinge for rapid and efficient detection and enrichment of CAR T cells

Immunotherapy including chimeric antigen receptor (CAR) T cell therapy has revolutionized modern cancer therapy and has achieved remarkable remission and survival rates for several malignancies with historically dismal outcomes. The hinge of the CAR connects the antigen binding to the transmembrane...

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Detalles Bibliográficos
Autores principales: Bister, Arthur, Ibach, Tabea, Haist, Corinna, Smorra, Denise, Roellecke, Katharina, Wagenmann, Martin, Scheckenbach, Kathrin, Gattermann, Norbert, Wiek, Constanze, Hanenberg, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640169/
https://www.ncbi.nlm.nih.gov/pubmed/34901395
http://dx.doi.org/10.1016/j.omto.2021.11.003