Exosomal lncRNA UCA1 Derived From Pancreatic Stellate Cells Promotes Gemcitabine Resistance in Pancreatic Cancer via the SOCS3/EZH2 Axis

OBJECTIVE: Pancreatic cancer is associated with poor prognosis and dismal survival rates. This study aims to investigate roles of lncRNA UCA1-loaded exosomes secreted by pancreatic stellate cells (PSCs) in Gemcitabine (Gem) resistance of pancreatic cancer under hypoxia, which involves the methylatio...

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Detalles Bibliográficos
Autores principales: Chi, Yuan, Xin, He, Liu, Zhaoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640181/
https://www.ncbi.nlm.nih.gov/pubmed/34868904
http://dx.doi.org/10.3389/fonc.2021.671082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640181/
https://www.ncbi.nlm.nih.gov/pubmed/34868904
http://dx.doi.org/10.3389/fonc.2021.671082

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