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MCC950 Ameliorates Acute Liver Injury Through Modulating Macrophage Polarization and Myeloid-Derived Suppressor Cells Function

Acute liver injury (ALI) raises high mortality rates due to a rapid pathological process. MCC950, a highly selective nod-like receptor family pyrin domain containing 3 (NLRP3) inhibitor, has already been reported to show strong hepatoprotective effects in many different liver diseases. In this study...

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Detalles Bibliográficos
Autores principales: Yan, Wei, Shen, Yingchun, Huang, Jinny, Lu, Ling, Zhang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640184/
https://www.ncbi.nlm.nih.gov/pubmed/34869447
http://dx.doi.org/10.3389/fmed.2021.752223