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PEGylated Doxorubicin Prodrug-Forming Reduction-Sensitive Micelles With High Drug Loading and Improved Anticancer Therapy

Significant efforts on the design and development of advanced drug delivery systems for targeted cancer chemotherapy continue to be a major challenge. Here, we reported a kind of reduction-responsive PEGylated doxorubicin (DOX) prodrug via the simple esterification and amidation reactions, which sel...

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Detalles Bibliográficos
Autores principales: Wang, Dongdong, Zhang, Xiaoyi, Xu, Bingbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640247/
https://www.ncbi.nlm.nih.gov/pubmed/34869293
http://dx.doi.org/10.3389/fbioe.2021.781982