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Gating and Regulatory Mechanisms of TMEM16 Ion Channels and Scramblases

The transmembrane protein 16 (TMEM16) family consists of Ca(2+)-activated ion channels and Ca(2+)-activated phospholipid scramblases (CaPLSases) that passively flip-flop phospholipids between the two leaflets of the membrane bilayer. Owing to their diverse functions, TMEM16 proteins have been implic...

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Detalles Bibliográficos
Autores principales: Le, Son C., Liang, Pengfei, Lowry, Augustus J., Yang, Huanghe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640346/
https://www.ncbi.nlm.nih.gov/pubmed/34867487
http://dx.doi.org/10.3389/fphys.2021.787773