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Expression and Functional Roles of Eukaryotic Initiation Factor 4A Family Proteins in Human Cancers

The dysregulation of mRNA translation is common in malignancies and may lead to tumorigenesis and progression. Eukaryotic initiation factor 4A (eIF4A) proteins are essential for translation, exhibit bidirectional RNA helicase function, and act as RNA-dependent ATPases. In this review, we explored th...

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Detalles Bibliográficos
Autores principales: Xue, Chen, Gu, Xinyu, Li, Ganglei, Bao, Zhengyi, Li, Lanjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640450/
https://www.ncbi.nlm.nih.gov/pubmed/34869305
http://dx.doi.org/10.3389/fcell.2021.711965