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(+)-Dehydrovomifoliol Alleviates Oleic Acid-Induced Lipid Accumulation in HepG2 Cells via the PPARα–FGF21 Pathway

An overload of hepatic fatty acids, such as oleic acid is a key trigger of non-alcoholic fatty liver disease (NAFLD). Here, we investigated whether Artemisia frigida, a valuable traditional medicine used to treat various diseases, could mitigate OA-induced lipid accumulation in HepG2 cells. Then, to...

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Detalles Bibliográficos
Autores principales: Xi, Yiyuan, Zheng, Jujia, Xie, Wei, Xu, Xiangwei, Cho, Namki, Zhou, Xudong, Yu, Xiaomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640464/
https://www.ncbi.nlm.nih.gov/pubmed/34867358
http://dx.doi.org/10.3389/fphar.2021.750147