Cargando…

(+)-Dehydrovomifoliol Alleviates Oleic Acid-Induced Lipid Accumulation in HepG2 Cells via the PPARα–FGF21 Pathway

An overload of hepatic fatty acids, such as oleic acid is a key trigger of non-alcoholic fatty liver disease (NAFLD). Here, we investigated whether Artemisia frigida, a valuable traditional medicine used to treat various diseases, could mitigate OA-induced lipid accumulation in HepG2 cells. Then, to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xi, Yiyuan, Zheng, Jujia, Xie, Wei, Xu, Xiangwei, Cho, Namki, Zhou, Xudong, Yu, Xiaomin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640464/ https://www.ncbi.nlm.nih.gov/pubmed/34867358 http://dx.doi.org/10.3389/fphar.2021.750147

Ejemplares similares

Resveratrol Alleviates Dextran Sulfate Sodium-Induced Acute Ulcerative Colitis in Mice by Mediating PI3K/Akt/VEGFA Pathway
por: Zhu, Fang, et al.
Publicado: (2021)

Nuciferine downregulates Per-Arnt-Sim kinase expression during its alleviation of lipogenesis and inflammation on oleic acid-induced hepatic steatosis in HepG(2) cells
por: Zhang, Dan-Dan, et al.
Publicado: (2015)

The effect of chitooligosaccharides on oleic acid-induced lipid accumulation in HepG(2) cells
por: Cao, Peiqiu, et al.
Publicado: (2016)

Ginkgolide C reduced oleic acid-induced lipid accumulation in HepG2 cells
por: Huang, Wen-Chung, et al.
Publicado: (2018)

Effects of three different formulae of Gamisoyosan on lipid accumulation induced by oleic acid in HepG2 cells
por: Go, Hiroe, et al.
Publicado: (2017)

Kaempferol and Kaempferide Attenuate Oleic Acid-Induced Lipid Accumulation and Oxidative Stress in HepG2 Cells
por: Tie, Fangfang, et al.
Publicado: (2021)

Dehydrovomifoliol Alleviates Nonalcoholic Fatty Liver Disease via the E2F1/AKT/mTOR Axis: Pharmacophore Modeling and Molecular Docking Study
por: Ma, Ji, et al.
Publicado: (2023)

Taurine alleviated hepatic steatosis in oleic acid-treated-HepG2 cells and rats fed a high-fat diet
por: Song, Qi, et al.
Publicado: (2023)

Self-assembled FGF21 nanoparticles alleviate drug-induced acute liver injury
por: Huang, Zhiwei, et al.
Publicado: (2023)

Impairment of Mitochondrial Biogenesis and Dynamics Involved in Isoniazid-Induced Apoptosis of HepG2 Cells Was Alleviated by p38 MAPK Pathway
por: Zhang, Tianguang, et al.
Publicado: (2017)

Effect of Toxicants on Fatty Acid Metabolism in HepG2 Cells
por: Grünig, David, et al.
Publicado: (2018)

Effects of dehydroabietic acid on nontarget lipidomics and proteomics of HepG2
por: Xiahou, Zhikai, et al.
Publicado: (2022)

Pinus densiflora Sieb. et Zucc. Alleviates Lipogenesis and Oxidative Stress during Oleic Acid-Induced Steatosis in HepG2 Cells
por: Hwang, Yu-Jin, et al.
Publicado: (2014)

Astragaloside IV Inhibits Triglyceride Accumulation in Insulin-Resistant HepG2 Cells via AMPK-Induced SREBP-1c Phosphorylation
por: Wang, Chunyi, et al.
Publicado: (2018)

Acteoside From Ligustrum robustum (Roxb.) Blume Ameliorates Lipid Metabolism and Synthesis in a HepG2 Cell Model of Lipid Accumulation
por: Sun, Le, et al.
Publicado: (2019)

Zanthoxylum ailanthoides Suppresses Oleic Acid-Induced Lipid Accumulation through an Activation of LKB1/AMPK Pathway in HepG2 Cells
por: Kwon, Eun-Bin, et al.
Publicado: (2018)

Corrigendum to “Zanthoxylum ailanthoides Suppresses Oleic Acid-Induced Lipid Accumulation through an Activation of LKB1/AMPK Pathway in HepG2 Cells”
por: Kwon, Eun-Bin, et al.
Publicado: (2019)

Sensitization effect of kaempferol from persimmon leaves on HepG2 hepatoma cells with ABT-199 resistance and its molecular mechanisms
por: Chen, Li, et al.
Publicado: (2022)

Transcriptome Analyses of the Anti-Proliferative Effects of 20(S)-Ginsenoside Rh2 on HepG2 Cells
por: Zhang, Ji, et al.
Publicado: (2019)

Differential Effects of Oleic and Palmitic Acids on Lipid Droplet-Mitochondria Interaction in the Hepatic Cell Line HepG2
por: Eynaudi, Andrea, et al.
Publicado: (2021)

High Concentrations of Rosiglitazone Reduce mRNA and Protein Levels of LRP1 in HepG2 Cells
por: Rondón-Ortiz, Alejandro N., et al.
Publicado: (2017)

Lycorine Induces Mitochondria-Dependent Apoptosis in Hepatoblastoma HepG2 Cells Through ROCK1 Activation
por: Liu, Wu-yi, et al.
Publicado: (2019)

Berberine Improves Glucose and Lipid Metabolism in HepG2 Cells Through AMPKα1 Activation
por: Ren, Gang, et al.
Publicado: (2020)

Rhizosphere Bacterium Rhodococcus sp. P1Y Metabolizes Abscisic Acid to Form Dehydrovomifoliol
por: Yuzikhin, Oleg S., et al.
Publicado: (2021)

Rosmarinic acid attenuates hepatic steatosis by modulating ER stress and autophagy in oleic acid-induced HepG2 cells
por: Balachander, Govindaraj Jayanthy, et al.
Publicado: (2018)

Hepatoprotective Effect of Steroidal Glycosides From Dioscorea villosa on Hydrogen Peroxide-Induced Hepatotoxicity in HepG2 Cells
por: Siddiqui, Maqsood A., et al.
Publicado: (2018)

A Novel Indolizine Derivative Induces Apoptosis Through the Mitochondria p53 Pathway in HepG2 Cells
por: Liu, Yushuang, et al.
Publicado: (2019)

The potential function and clinical application of FGF21 in metabolic diseases
por: Chen, Zhiwei, et al.
Publicado: (2022)

A Controlled Fermented Samjunghwan Herbal Formula Ameliorates Non-alcoholic Hepatosteatosis in HepG2 Cells and OLETF Rats
por: Ansari, AbuZar, et al.
Publicado: (2018)

Synthesis of Chalcone Derivatives: Inducing Apoptosis of HepG2 Cells via Regulating Reactive Oxygen Species and Mitochondrial Pathway
por: Zhu, Hongtian, et al.
Publicado: (2019)

Hydroxyethyl Starch Curcumin Enhances Antiproliferative Effect of Curcumin Against HepG2 Cells via Apoptosis and Autophagy Induction
por: Jiang, Linhai, et al.
Publicado: (2021)

Investigation of the Effect of Exendin-4 on Oleic Acid-Induced Steatosis in HepG2 Cells Using Fourier Transform Infrared Spectroscopy
por: Khalifa, Olfa, et al.
Publicado: (2022)

FGF9 Alleviates the Fatty Liver Phenotype by Regulating Hepatic Lipid Metabolism
por: Zhao, Fanrong, et al.
Publicado: (2022)

PDE7B is involved in nandrolone decanoate hydrolysis in liver cytosol and its transcription is up-regulated by androgens in HepG2
por: Strahm, Emmanuel, et al.
Publicado: (2014)

Agrimonolide and Desmethylagrimonolide Induced HO-1 Expression in HepG2 Cells through Nrf2-Transduction and p38 Inactivation
por: Chen, Lei, et al.
Publicado: (2017)

6-Gingerol Regulates Hepatic Cholesterol Metabolism by Up-regulation of LDLR and Cholesterol Efflux-Related Genes in HepG2 Cells
por: Li, Xiao, et al.
Publicado: (2018)

17β-Estradiol Promotes Apoptosis of HepG2 Cells Caused by Oxidative Stress by Increasing Foxo3a Phosphorylation
por: Guo, Yusheng, et al.
Publicado: (2021)

GPR21 Inhibition Increases Glucose-Uptake in HepG2 Cells
por: Kinsella, Gemma K., et al.
Publicado: (2021)

Statins Activate Human PPARα Promoter and Increase PPARα mRNA Expression and Activation in HepG2 Cells
por: Seo, Makoto, et al.
Publicado: (2008)

The idiosyncratic drug-induced gene expression changes in HepG2 cells
por: Jiang, J., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_iotpqfam62svfj2v7jqknovhgm