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Murine cerebral organoids develop network of functional neurons and hippocampal brain region identity
Brain organoids are in vitro three-dimensional (3D) self-organized neural structures, which can enable disease modeling and drug screening. However, their use for standardized large-scale drug screening studies is limited by their high batch-to-batch variability, long differentiation time (10–20 wee...
Autores principales: | , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640475/ https://www.ncbi.nlm.nih.gov/pubmed/34901791 http://dx.doi.org/10.1016/j.isci.2021.103438 |