Murine cerebral organoids develop network of functional neurons and hippocampal brain region identity

Brain organoids are in vitro three-dimensional (3D) self-organized neural structures, which can enable disease modeling and drug screening. However, their use for standardized large-scale drug screening studies is limited by their high batch-to-batch variability, long differentiation time (10–20 wee...

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Detalles Bibliográficos
Autores principales: Ciarpella, Francesca, Zamfir, Raluca Georgiana, Campanelli, Alessandra, Ren, Elisa, Pedrotti, Giulia, Bottani, Emanuela, Borioli, Andrea, Caron, Davide, Di Chio, Marzia, Dolci, Sissi, Ahtiainen, Annika, Malpeli, Giorgio, Malerba, Giovanni, Bardoni, Rita, Fumagalli, Guido, Hyttinen, Jari, Bifari, Francesco, Palazzolo, Gemma, Panuccio, Gabriella, Curia, Giulia, Decimo, Ilaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640475/
https://www.ncbi.nlm.nih.gov/pubmed/34901791
http://dx.doi.org/10.1016/j.isci.2021.103438

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