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Computational modeling of unphosphorylated CtrA:Cori binding in the Caulobacter cell cycle

In the alphaproteobacterium, Caulobacter crescentus, phosphorylated CtrA (CtrA∼P), a master regulatory protein, binds directly to the chromosome origin (Cori) to inhibit DNA replication. Using a mathematical model of CtrA binding at Cori site [d], we provide computational evidence that CtrA(U) can d...

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Detalles Bibliográficos
Autores principales: Weston, Bronson R., Tyson, John J., Cao, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640480/
https://www.ncbi.nlm.nih.gov/pubmed/34901785
http://dx.doi.org/10.1016/j.isci.2021.103413