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Computational modeling of unphosphorylated CtrA:Cori binding in the Caulobacter cell cycle
In the alphaproteobacterium, Caulobacter crescentus, phosphorylated CtrA (CtrA∼P), a master regulatory protein, binds directly to the chromosome origin (Cori) to inhibit DNA replication. Using a mathematical model of CtrA binding at Cori site [d], we provide computational evidence that CtrA(U) can d...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640480/ https://www.ncbi.nlm.nih.gov/pubmed/34901785 http://dx.doi.org/10.1016/j.isci.2021.103413 |