A Novel ELISA-Based Peptide Biosensor Assay for Screening ABL1 Activity in vitro: A Challenge for Precision Therapy in BCR-ABL1 and BCR-ABL1 Like Leukemias

The pathogenic role of the overactivated ABL1 tyrosine kinase (TK) pathway is well recognized in some forms of BCR-ABL1 like acute lymphoblastic leukemia (ALL); TK inhibitors represent a useful therapeutic choice in these patients who respond poorly to conventional chemotherapy. Here we report a nov...

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Detalles Bibliográficos
Autores principales: Montecchini, Oksana, Braidotti, Stefania, Franca, Raffaella, Zudeh, Giulia, Boni, Christian, Sorio, Claudio, Toffoletti, Eleonora, Rabusin, Marco, Tommasini, Alberto, Decorti, Giuliana, Stocco, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640483/
https://www.ncbi.nlm.nih.gov/pubmed/34867354
http://dx.doi.org/10.3389/fphar.2021.749361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640483/
https://www.ncbi.nlm.nih.gov/pubmed/34867354
http://dx.doi.org/10.3389/fphar.2021.749361

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