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Layer-specific stem cell differentiation in tri-layered tissue engineering biomaterials: Towards development of a single-stage cell-based approach for osteochondral defect repair

Successful repair of osteochondral defects is challenging, due in part to their complex gradient nature. Tissue engineering approaches have shown promise with the development of layered scaffolds that aim to promote cartilage and bone regeneration within the defect. The clinical potential of implant...

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Detalles Bibliográficos
Autores principales: Levingstone, Tanya J., Moran, Conor, Almeida, Henrique V., Kelly, Daniel J., O'Brien, Fergal J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640516/
https://www.ncbi.nlm.nih.gov/pubmed/34901823
http://dx.doi.org/10.1016/j.mtbio.2021.100173