Estimation of Mycophenolic Acid Exposure in Heart Transplant Recipients by Population Pharmacokinetic and Limited Sampling Strategies

Purpose: The aim of this study is i) to establish a strategy to estimate the area under the curve of the dosing interval (AUC(0–12h)) of mycophenolic acid (MPA) in the heart transplant recipients and ii) to find the covariates that significantly affect the pharmacokinetics of MPA exposure. Methods:...

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Detalles Bibliográficos
Autores principales: Wang, Xipei, Wu, Yijin, Huang, Jinsong, Shan, Songgui, Mai, Mingjie, Zhu, Jiade, Yang, Min, Shang, Dewei, Wu, Zheng, Lan, Jinhua, Zhong, Shilong, Wu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640522/
https://www.ncbi.nlm.nih.gov/pubmed/34867352
http://dx.doi.org/10.3389/fphar.2021.748609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640522/
https://www.ncbi.nlm.nih.gov/pubmed/34867352
http://dx.doi.org/10.3389/fphar.2021.748609

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