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Estimation of Mycophenolic Acid Exposure in Heart Transplant Recipients by Population Pharmacokinetic and Limited Sampling Strategies
Purpose: The aim of this study is i) to establish a strategy to estimate the area under the curve of the dosing interval (AUC(0–12h)) of mycophenolic acid (MPA) in the heart transplant recipients and ii) to find the covariates that significantly affect the pharmacokinetics of MPA exposure. Methods:...
Autores principales: | Wang, Xipei, Wu, Yijin, Huang, Jinsong, Shan, Songgui, Mai, Mingjie, Zhu, Jiade, Yang, Min, Shang, Dewei, Wu, Zheng, Lan, Jinhua, Zhong, Shilong, Wu, Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640522/ https://www.ncbi.nlm.nih.gov/pubmed/34867352 http://dx.doi.org/10.3389/fphar.2021.748609 |
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