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TELO-SCOPE study: a randomised, double-blind, placebo-controlled, phase 2 trial of danazol for short telomere related pulmonary fibrosis

INTRODUCTION: Recent discoveries have identified shortened telomeres and related mutations in people with pulmonary fibrosis (PF). There is evidence to suggest that androgens, including danazol, may be effective in lengthening telomeres in peripheral blood cells. This study aims to assess the safety...

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Detalles Bibliográficos
Autores principales: Mackintosh, John A, Pietsch, Maria, Lutzky, Viviana, Enever, Debra, Bancroft, Sandra, Apte, Simon H, Tan, Maxine, Yerkovich, Stephanie T, Dickinson, Joanne L, Pickett, Hilda A, Selvadurai, Hiran, Grainge, Christopher, Goh, Nicole S, Hopkins, Peter, Glaspole, Ian, Reynolds, Paul N, Wrobel, Jeremy, Jaffe, Adam, Corte, Tamera J, Chambers, Daniel C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640666/
https://www.ncbi.nlm.nih.gov/pubmed/34857525
http://dx.doi.org/10.1136/bmjresp-2021-001127