Th17 cell master transcription factor RORC2 regulates HIV-1 gene expression and viral outgrowth

Among CD4(+) T cells, T helper 17 (Th17) cells are particularly susceptible to HIV-1 infection and are depleted from mucosal sites, which causes damage to the gut barrier, resulting in a microbial translocation-induced systemic inflammation, a hallmark of disease progression. Furthermore, a proporti...

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Detalles Bibliográficos
Autores principales: Wiche Salinas, Tomas Raul, Zhang, Yuwei, Sarnello, Daniele, Zhyvoloup, Alexander, Marchand, Laurence Raymond, Fert, Augustine, Planas, Delphine, Lodha, Manivel, Chatterjee, Debashree, Karwacz, Katarzyna, Oxenford, Sally, Routy, Jean-Pierre, Irlbeck, David, Amrine-Madsen, Heather, Ancuta, Petronela, Fassati, Ariberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640723/
https://www.ncbi.nlm.nih.gov/pubmed/34819367
http://dx.doi.org/10.1073/pnas.2105927118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640723/
https://www.ncbi.nlm.nih.gov/pubmed/34819367
http://dx.doi.org/10.1073/pnas.2105927118

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