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Hyperglycemia-induced increasing of RELB/circ_0008590 in NF-κB pathway is repressed by miR-1243 in human retinal microvascular endothelial cells

BACKGROUND: To investigate the abnormal expression of circ_0008590 and its parent gene, reticuloendotheliosis viral oncogene related B (RELB) in human retinal microvascular endothelial cells (hRECs) in hyperglycemia and the potential mechanism. METHODS: The levels of RELB, circ_0008590, and miR-1243...

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Detalles Bibliográficos
Autores principales: Shao, Jun, Cai, Jiping, Yao, Yong, Zhu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640898/
https://www.ncbi.nlm.nih.gov/pubmed/34926668
http://dx.doi.org/10.21037/atm-21-5562