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Ccp1-Ndc80 switch at the N terminus of CENP-T regulates kinetochore assembly

Kinetochores, a protein complex assembled on centromeres, mediate chromosome segregation. In most eukaryotes, centromeres are epigenetically specified by the histone H3 variant CENP-A. CENP-T, an inner kinetochore protein, serves as a platform for the assembly of the outer kinetochore Ndc80 complex...

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Detalles Bibliográficos
Autores principales: Dong, Qianhua, Liu, Xue-lei, Wang, Xiao-hui, Zhao, Yu, Chen, Yu-hang, Li, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640933/
https://www.ncbi.nlm.nih.gov/pubmed/34810257
http://dx.doi.org/10.1073/pnas.2104459118