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Proliferation of Tau 304–380 Fragment Aggregates through Autocatalytic Secondary Nucleation
[Image: see text] The self-assembly of the protein tau into neurofibrillary tangles is one of the hallmarks of Alzheimer’s disease and related tauopathies. Still, the molecular mechanism of tau aggregation is largely unknown. This problem may be addressed by systematically obtaining reproducible in...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640994/ https://www.ncbi.nlm.nih.gov/pubmed/34783519 http://dx.doi.org/10.1021/acschemneuro.1c00454 |