Proliferation of Tau 304–380 Fragment Aggregates through Autocatalytic Secondary Nucleation

[Image: see text] The self-assembly of the protein tau into neurofibrillary tangles is one of the hallmarks of Alzheimer’s disease and related tauopathies. Still, the molecular mechanism of tau aggregation is largely unknown. This problem may be addressed by systematically obtaining reproducible in...

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Detalles Bibliográficos
Autores principales: Rodriguez Camargo, Diana C., Sileikis, Eimantas, Chia, Sean, Axell, Emil, Bernfur, Katja, Cataldi, Rodrigo L., Cohen, Samuel I. A., Meisl, Georg, Habchi, Johnny, Knowles, Tuomas P. J., Vendruscolo, Michele, Linse, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640994/
https://www.ncbi.nlm.nih.gov/pubmed/34783519
http://dx.doi.org/10.1021/acschemneuro.1c00454

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