Novel Thienopyrimidine-Based PET Tracers for P2Y(12) Receptor Imaging in the Brain

[Image: see text] The P2Y(12) receptor (P2Y(12)R) is uniquely expressed on microglia in the brain, and its expression level directly depends on the microglial activation state. Therefore, P2Y(12)R provides a promising imaging marker for distinguishing the pro- and anti-inflammatory microglial phenot...

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Detalles Bibliográficos
Autores principales: van der Wildt, Berend, Janssen, Bieneke, Pekošak, Aleksandra, Stéen, E. Johanna L., Schuit, Robert C., Kooijman, Esther J. M., Beaino, Wissam, Vugts, Danielle J., Windhorst, Albert D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640995/
https://www.ncbi.nlm.nih.gov/pubmed/34757711
http://dx.doi.org/10.1021/acschemneuro.1c00641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640995/
https://www.ncbi.nlm.nih.gov/pubmed/34757711
http://dx.doi.org/10.1021/acschemneuro.1c00641

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