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Structural and Biochemical Characterization of Cysteinylation in Broadly Neutralizing Antibodies to HIV-1

Antibodies with exceptional breadth and potency have been elicited in some individuals during natural HIV-1 infection. Elicitation and affinity maturation of broadly neutralizing antibodies (bnAbs) is therefore the central goal of HIV-1 vaccine development. The functional properties of bnAbs also ma...

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Detalles Bibliográficos
Autores principales: Omorodion, Oluwarotimi, Wilson, Ian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641059/
https://www.ncbi.nlm.nih.gov/pubmed/34666044
http://dx.doi.org/10.1016/j.jmb.2021.167303