Cargando…
Structural and Biochemical Characterization of Cysteinylation in Broadly Neutralizing Antibodies to HIV-1
Antibodies with exceptional breadth and potency have been elicited in some individuals during natural HIV-1 infection. Elicitation and affinity maturation of broadly neutralizing antibodies (bnAbs) is therefore the central goal of HIV-1 vaccine development. The functional properties of bnAbs also ma...
Autores principales: | Omorodion, Oluwarotimi, Wilson, Ian A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641059/ https://www.ncbi.nlm.nih.gov/pubmed/34666044 http://dx.doi.org/10.1016/j.jmb.2021.167303 |
Ejemplares similares
-
Stapled HIV-1 Peptides Recapitulate Antigenic Structures and Engage Broadly Neutralizing Antibodies
por: Bird, Gregory H., et al.
Publicado: (2014) -
Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies
por: Joyce, Collin, et al.
Publicado: (2023) -
Structural basis of broad HIV neutralization by a vaccine-induced cow antibody
por: Stanfield, Robyn L., et al.
Publicado: (2020) -
Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design
por: Rantalainen, Kimmo, et al.
Publicado: (2018) -
Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01
por: Pinto, Dora, et al.
Publicado: (2019)