Inhibition of the immunoproteasome LMP2 ameliorates ischemia/hypoxia-induced blood–brain barrier injury through the Wnt/β-catenin signalling pathway

BACKGROUND: Disruption of the blood–brain barrier (BBB) after a stroke can lead to brain injury and neurological impairment. Previous work confirmed the involvement of the immunoproteasome subunit of low molecular mass peptide 2 (LMP2) in the pathophysiology of ischemia stroke. However, the relation...

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Detalles Bibliográficos
Autores principales: Chen, Xing-Yong, Wan, Shao-Fen, Yao, Nan-Nan, Lin, Ze-Jing, Mao, Yan-Guang, Yu, Xiao-Hua, Wang, Yin-Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641178/
https://www.ncbi.nlm.nih.gov/pubmed/34857032
http://dx.doi.org/10.1186/s40779-021-00356-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641178/
https://www.ncbi.nlm.nih.gov/pubmed/34857032
http://dx.doi.org/10.1186/s40779-021-00356-x

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