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Inhibition of the immunoproteasome LMP2 ameliorates ischemia/hypoxia-induced blood–brain barrier injury through the Wnt/β-catenin signalling pathway
BACKGROUND: Disruption of the blood–brain barrier (BBB) after a stroke can lead to brain injury and neurological impairment. Previous work confirmed the involvement of the immunoproteasome subunit of low molecular mass peptide 2 (LMP2) in the pathophysiology of ischemia stroke. However, the relation...
Autores principales: | Chen, Xing-Yong, Wan, Shao-Fen, Yao, Nan-Nan, Lin, Ze-Jing, Mao, Yan-Guang, Yu, Xiao-Hua, Wang, Yin-Zhou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641178/ https://www.ncbi.nlm.nih.gov/pubmed/34857032 http://dx.doi.org/10.1186/s40779-021-00356-x |
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