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Exploring cell-specific miRNA regulation with single-cell miRNA-mRNA co-sequencing data

BACKGROUND: Existing computational methods for studying miRNA regulation are mostly based on bulk miRNA and mRNA expression data. However, bulk data only allows the analysis of miRNA regulation regarding a group of cells, rather than the miRNA regulation unique to individual cells. Recent advance in...

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Detalles Bibliográficos
Autores principales: Zhang, Junpeng, Liu, Lin, Xu, Taosheng, Zhang, Wu, Zhao, Chunwen, Li, Sijing, Li, Jiuyong, Rao, Nini, Le, Thuc Duy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641245/
https://www.ncbi.nlm.nih.gov/pubmed/34856921
http://dx.doi.org/10.1186/s12859-021-04498-6