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Kinetochore-bound Mps1 regulates kinetochore–microtubule attachments via Ndc80 phosphorylation

Dividing cells detect and correct erroneous kinetochore–microtubule attachments during mitosis, thereby avoiding chromosome missegregation. The Aurora B kinase phosphorylates microtubule-binding elements specifically at incorrectly attached kinetochores, promoting their release and providing another...

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Detalles Bibliográficos
Autores principales: Sarangapani, Krishna K., Koch, Lori B., Nelson, Christian R., Asbury, Charles L., Biggins, Sue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641409/
https://www.ncbi.nlm.nih.gov/pubmed/34647959
http://dx.doi.org/10.1083/jcb.202106130