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Kinetochore-bound Mps1 regulates kinetochore–microtubule attachments via Ndc80 phosphorylation
Dividing cells detect and correct erroneous kinetochore–microtubule attachments during mitosis, thereby avoiding chromosome missegregation. The Aurora B kinase phosphorylates microtubule-binding elements specifically at incorrectly attached kinetochores, promoting their release and providing another...
Autores principales: | Sarangapani, Krishna K., Koch, Lori B., Nelson, Christian R., Asbury, Charles L., Biggins, Sue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641409/ https://www.ncbi.nlm.nih.gov/pubmed/34647959 http://dx.doi.org/10.1083/jcb.202106130 |
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