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New amino acid substitution matrix brings sequence alignments into agreement with structure matches
Protein sequence matching presently fails to identify many structures that are highly similar, even when they are known to have the same function. The high packing densities in globular proteins lead to interdependent substitutions, which have not previously been considered for amino acid similariti...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641535/ https://www.ncbi.nlm.nih.gov/pubmed/33469973 http://dx.doi.org/10.1002/prot.26050 |