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Preparation of oridonin nanocrystals and study of their endocytosis and transcytosis behaviours on MDCK polarized epithelial cells

CONTEXT: Oridonin (ORI) has obvious anticancer effects, but its solubility is poor. Nanocrystal (NC) is a novel nano-drug delivery system for increasing bioavailability for ORI. However, the endocytosis and transcytosis behaviours of oridonin nanocrystals (ORI-NCs) through epithelial membrane are st...

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Detalles Bibliográficos
Autores principales: Sheng, Huagang, Zhang, Yuanyuan, Nai, Jijuan, Wang, Shaohua, Dai, Mengmeng, Lin, Guitao, Zhu, Liqiao, Zhang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641689/
https://www.ncbi.nlm.nih.gov/pubmed/32501184
http://dx.doi.org/10.1080/13880209.2020.1767160