Nuclear dengue virus NS5 antagonizes expression of PAF1-dependent immune response genes

Dengue virus (DENV) disruption of the innate immune response is critical to establish infection. DENV non-structural protein 5 (NS5) plays a central role in this disruption, such as antagonism of STAT2. We recently found that DENV serotype 2 (DENV2) NS5 interacts with Polymerase associated factor 1...

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Detalles Bibliográficos
Autores principales: Petit, Marine J., Kenaston, Matthew W., Pham, Oanh H., Nagainis, Ariana A., Fishburn, Adam T., Shah, Priya S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641875/
https://www.ncbi.nlm.nih.gov/pubmed/34797876
http://dx.doi.org/10.1371/journal.ppat.1010100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641875/
https://www.ncbi.nlm.nih.gov/pubmed/34797876
http://dx.doi.org/10.1371/journal.ppat.1010100

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