Control of tissue homeostasis, tumorigenesis, and degeneration by coupled bidirectional bistable switches

The Hippo-YAP/TAZ signaling pathway plays a critical role in tissue homeostasis, tumorigenesis, and degeneration disorders. The regulation of YAP/TAZ levels is controlled by a complex regulatory network, where several feedback loops have been identified. However, it remains elusive how these feedbac...

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Detalles Bibliográficos
Autores principales: Barra Avila, Diego, Melendez-Alvarez, Juan R., Tian, Xiao-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641876/
https://www.ncbi.nlm.nih.gov/pubmed/34797839
http://dx.doi.org/10.1371/journal.pcbi.1009606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641876/
https://www.ncbi.nlm.nih.gov/pubmed/34797839
http://dx.doi.org/10.1371/journal.pcbi.1009606

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