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Control of tissue homeostasis, tumorigenesis, and degeneration by coupled bidirectional bistable switches
The Hippo-YAP/TAZ signaling pathway plays a critical role in tissue homeostasis, tumorigenesis, and degeneration disorders. The regulation of YAP/TAZ levels is controlled by a complex regulatory network, where several feedback loops have been identified. However, it remains elusive how these feedbac...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8641876/ https://www.ncbi.nlm.nih.gov/pubmed/34797839 http://dx.doi.org/10.1371/journal.pcbi.1009606 |