Crystal structure of human METTL6, the m(3)C methyltransferase

In tRNA, the epigenetic m(3)C modification at position 32 in the anticodon loop is highly conserved in eukaryotes, which maintains the folding and basepairing functions of the anticodon. However, the responsible enzymes METTL2 and METTL6 were identified only in recent years. The loss of human METTL6...

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Detalles Bibliográficos
Autores principales: Chen, Ran, Zhou, Jie, Liu, Ling, Mao, Xue-Ling, Zhou, Xiaolong, Xie, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642396/
https://www.ncbi.nlm.nih.gov/pubmed/34862464
http://dx.doi.org/10.1038/s42003-021-02890-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642396/
https://www.ncbi.nlm.nih.gov/pubmed/34862464
http://dx.doi.org/10.1038/s42003-021-02890-9

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