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Crystal structure of human METTL6, the m(3)C methyltransferase
In tRNA, the epigenetic m(3)C modification at position 32 in the anticodon loop is highly conserved in eukaryotes, which maintains the folding and basepairing functions of the anticodon. However, the responsible enzymes METTL2 and METTL6 were identified only in recent years. The loss of human METTL6...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642396/ https://www.ncbi.nlm.nih.gov/pubmed/34862464 http://dx.doi.org/10.1038/s42003-021-02890-9 |