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Hippo signaling suppresses tumor cell metastasis via a Yki-Src42A positive feedback loop

Metastasis is an important cause of death from malignant tumors. It is of great significance to explore the molecular mechanism of metastasis for the development of anti-cancer drugs. Here, we find that the Hippo pathway hampers tumor cell metastasis in vivo. Silence of hpo or its downstream wts pro...

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Detalles Bibliográficos
Autores principales: Ding, Yan, Wang, Guiping, Zhan, Meixiao, Sun, Xiaohan, Deng, Yanran, Zhao, Yunhe, Liu, Bin, Liu, Qingxin, Wu, Shian, Zhou, Zizhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642408/
https://www.ncbi.nlm.nih.gov/pubmed/34862372
http://dx.doi.org/10.1038/s41419-021-04423-y