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Investigating genetically mimicked effects of statins via HMGCR inhibition on immune-related diseases in men and women using Mendelian randomization

Statins have been suggested as a potential treatment for immune-related diseases. Conversely, statins might trigger auto-immune conditions. To clarify the role of statins in allergic diseases and auto-immune diseases, we conducted a Mendelian randomization (MR) study. Using established genetic instr...

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Detalles Bibliográficos
Autores principales: Yang, Guoyi, Schooling, C. Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642420/
https://www.ncbi.nlm.nih.gov/pubmed/34862478
http://dx.doi.org/10.1038/s41598-021-02981-x